Click on title to go to lab archived copy of each publication


Su H, Cheng Z, Huang J, Lin J, Copenhaver GP, Ma H, Wang Y (2017) Arabidopsis RAD51, RAD51C and XRCC3 proteins form a complex and facilitate RAD51 localization on chromosomes for meiotic recombinationPLOS Genetics 13(5): e1006827.

Modliszewski JL and Copenhaver GP (2017) Meiotic Recombination Gets Stressed Out: CO Frequency is Plastic Under PressureCurrent Opinion in Plant Biology 36: 95–102.

Barsh GS, Bergman CM, Brown CD, Singh ND, Copenhaver GP (2016) Bringing PLOS Genetics Editors to Preprint Servers.  PLOS Genetics 12(12): e1006448. doi:10.1371/journal.pgen.1006448

Huang J, Copenhaver GP, Hong M, Wang Y (2016) New Insights into the role of DNA synthesis in meiotic recombination.  Science Bulletin 61(16): 1260-1269.  doi: 10.1007/s11434-016-1126-7

Choi K, Reinhard C, Serra H, Ziolkowski PA, Underwood C, Zhao X, Hardcastle TJ, Yelina NE, Griffin C, Jackson M, Mézard C, McVean G, Copenhaver GP, and Henderson IR (2016) Recombination rate heterogeneity within Arabidopsis disease resistance genes.  PLOS Genetics 12(7): e1006179. doi: 10.1371/journal.pgen.1006179.

Barsh GS, Copenhaver GP (2016) The Language of Genetics in the Interviews of Jane Gitschier.  PLOS Genetics 12(6): e1006115. doi:10.1371/journal.pgen.1006115

Niu B, Wang L, Zhang L, Ren D, Ren R, Copenhaver GP, Ma H, Wang Y (2015) The Arabidopsis CDC20.1 Gene is Required for Normal Meiotic Spindle Assembly and Chromosome Segregation.  The Plant Cell 27(12): 3367-3382. doi:

Barsh GS, Cooper GM, Copenhaver GP, Gibson G, McCarthy MI, Tang H, Williams SM (2015) PLOS Genetics Data Sharing Policy: In Pursuit of Functional Utility.  PLOS Genetics e1005716. doi:10.1371/journal.pgen.1005716

Copenhaver GP and Barsh GS (2015) A Decad(e) of reasons to contribute to a PLOS Community-run Journal.  PLOS Genetics 11(10): e1005557. doi:10.1371/journal.pgen.1005557

Huang J, Cheng Z, Wang C, Hong Y, Su H, Wang J, Copenhaver GP, Ma H, Wang Y (2015) Formation of interference-sensitive meiotic crossovers requires sufficient DNA leading strand elongation.  Proc. Natl. Acad. Sci. USA 112(40):12534-9. doi: 10.1073/pnas.1507165112

Modliszewski J and Copenhaver GP (2015) Meiotic recombination heats up.  New Phytologist 208: 295–297.  doi: 10.1111/nph.13618

Lambing C, Osman K, Nuntasoontorn K, West A, Higgins JD, Copenhaver GP, Yang J, Armstrong SJ, Mechtler K, Roitinger E, Franklin FCH (2015) Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers.  PLOS Genetics 11(7): e1005372. doi:10.1371/journal.pgen.1005372

Vara J, Sánchez-Morán E, Copenhaver GP, Santos JL, Pradillo M (2015) Analysis of the Relationships between DNA Double-Strand Breaks, Synaptonemal Complex and Crossovers Using the Atfas1-4 Mutant.  PLOS Genetics 11(7): e1005301.  doi:10.1371/journal.pgen.1005301 *

* This work was featured as the “Issue Image” (the equivalent of the cover).

Ziolkowski PA, Berchowitz LE, Lambing C, Yelina NE, Zhao X, Kelly KA, Choi K, Ziolkowska L, June V, Sanchez-Moran E, Franklin C, Copenhaver GP, Henderson IR (2015) Juxtaposition of heterozygosity and homozygosity during meiosis causes reciprocal crossover remodeling via interference.  eLife 2015;4:e03708.  doi:

Qi J, Chen Y, Copenhaver GP, Ma H (2014) Detection of Genomic Variations and DNA Polymorphisms and Impact on Analysis of Meiotic Recombination and Genetic Mapping.  Proc. Natl. Acad. Sci. USA.  111(27): 10007–10012.  doi:10.1073/pnas.1321897111 *

* This work was featured in an “In This Issue” highlight (doi: 10.1073/iti2714111)

Lu P, Wijeratne AJ, Wang Z, Copenhaver GP,  Ma H (2014) Arabidopsis PTD Is Required For Type I Crossover Formation and Affects Recombination Frequency in Two Different Chromosomal Regions.  Journal of Genetics and Genomics.  41(3):165-175.  doi: 10.1016/j.jgg.2014.02.001

Yelina NE, Ziolkowski PA, Miller N, Zhao X, Kelly KA, Muñoz DF, Mann DJ, Copenhaver GP & Henderson IR (2013) High-throughput analysis of meiotic crossover frequency and interference via flow cytometry of fluorescent pollen in Arabidopsis thaliana.  Nature Protocols. 8(11): 2119–2134.  doi:10.1038/nprot.2013.131

Choi K, Zhao X, Kelly KA, Venn O, Higgins J, Yelina N, Hardcastle T, Ziolkowski P, Copenhaver GP, Franklin C, McVean G, and Henderson IR (2013) Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promotersNature Genetics. 45(11):1327-36. doi: 10.1038/ng.2766

Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR,  Brown W, Cheeseman IM, Choo KHA, Copenhaver GP, DeLuca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LET, Karpen G, Kops GJP, Lampson MA, Lens SM, Losada A, Luger AK, H. Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O’Neill RJ, Salmon ED, Scott K, Straight AF, Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K and Cleveland DW (2013) Esperanto for Histones: CENP-A, not CenH3, is the centromeric histone H3 variant.  Chromosome Research 21: 101. doi:10.1007/s10577-013-9347-y

Wang Y, Cheng Z, Huang J, Shi Q, Hong Y, Copenhaver GP, Gong Z, Ma H (2012) The DNA Replication Factor RFC1 is Required for Interference-Sensitive Meiotic Crossovers in Arabidopsis thalianaPLoS Genetics 8(11): e1003039. doi:10.1371/journal.pgen.1003039

De Storme N, Copenhaver GP, Geelen D (2012) Production of diploid male gametes in Arabidopsis by cold-induced destabilization of post-meiotic radial microtubule arrays.  Plant Physiology, 160(4): 1808-1826.  doi: 10.1104/pp.112.208611

Sun Y, Ambrose JH, Haughey BS, Webster TD, Pierrie SN, Muñoz DF, Wellman EC, Cherian S, Lewis SM, Berchowitz LE and Copenhaver GP (2012) Deep Genome-wide measurement of meiotic gene conversion using tetrad analysis in Arabidopsis thaliana.  PLoS Genetics 8(10): e1002968. doi:10.1371/journal.pgen.1002968 *

* This work was featured as the “Issue Image” (the equivalent of the cover).  It was also recommended by Faculty of 1000. 

Yelina NE, Choi K, Chelysheva L, Macaulay M, de Snoo B, Wijnker E, Miller N, Drouaud J, Grelon M, Copenhaver GP, Mezard C, Kelly KA and Henderson IR (2012)  Epigenetic Remodeling of Meiotic Crossover Frequency in Arabidopsis thaliana DNA Methyltransferase MutantsPLoS Genetics 8(8): e1002844. doi:10.1371/journal.pgen.1002844

Barsh GS, Copenhaver GP, Gibson G, Williams SM (2012) Guidelines for genome-wide association studies.  PLoS Genetics 8(7) e1002812.doi:10.1371/journal.pgen.1002812.

Crismani W, Girard C, Forger N, Pradillo M, Santos JL, Chelyscheva L, Copenhaver GP, Horlow C and Mercier R (2012) FANCM Limits Meiotic Crossovers.  Science 336: 1588-1590. doi:10.1126/science.1220381 *

* This work was featured in the “This Week in Science” section in a highlight entitled “No Crossing Over” (Hurtley S, 2012, Science 336: 1480-1481).  It was also recommended by Faculty of 1000.

 Luo S, Mach JM, Abramson BW, Ramirez R, Schurr R, Barone P, Copenhaver GP and Folkerts O (2012) The Cotton Centromere Contains a Ty3-gypsy-like LTR Retroelement.  PLoS ONE 7(4): e35261. doi:10.1371/journal.pone.0035261

Roy B, Copenhaver GP, von Arnim AG (2011) Fluorescence-Tagged Transgenic Lines Reveal Genetic Defects in Pollen Growth – Application to the Eif3 Complex.  PLoS ONE 6(3): e17640.  doi:10.1371/journal.pone.0017640.

Gibson G, Copenhaver GP (2010) Consent and Internet-Enabled Human GenomicsPLoS Genetics 6(6): e1000965. doi:10.1371/journal.pgen.1000965.

d'Erfurth I, Cromer L, Jolivet S, Girard C, Horlow C, Sun Y, To JPC, Berchowitz LE, Copenhaver GP, Mercier R (2010) The CYCLIN-A CYCA1;2/TAM Is Required for the Meiosis I to Meiosis II Transition and Cooperates with OSD1 for the Prophase to First Meiotic Division TransitionPLoS Genetics 6(6): e1000989. doi:10.1371/journal.pgen.1000989.

Copenhaver GP & Preuss D (2010) Haploidy with histonesNature Biotechnology 28(5): 423-424.  doi:10.1038/nbt0510-423

Berchowitz LE, Copenhaver GP  (2010) Genetic interference: don’t stand so close to me.  Current Genomics 11:91-102. doi:10.2174/138920210790886835

Berchowitz LE, Hanlon SE, Lieb JD, Copenhaver GP (2009) A positive but complex association between meiotic double-strand break hotspots and open chromatin in Saccharomyces cerevisiae.  Genome Research 19:2245-2257. doi:10.1101/gr.096297.109 *

* This work was recommended by Faculty of 1000.

Barsh GS, Copenhaver GP (2009) Scientists ← Editors ← Scientists: Past, present, and future for PLoS Genetics.  PLoS Genet 5(7): e1000580. doi:10.1371/journal.pgen.1000580

Berchowitz LE and Copenhaver GP (2009) Visual Markers for Detecting Gene Conversion Directly in the Gametes of Arabidopsis thaliana.  In Meiosis Volume 1 Molecular and Genetic Methods, ed. Scott Keeney Volume 557 of the series Methods in Molecular Biology pp 99-114.  doi:10.1007/978-1-59745-527-5_8

Berchowitz LE and Copenhaver GP (2008) Division of Labor Among Meiotic Genes.  Nature Genetics 40:266-267.  doi:10.1038/ng0308-266

Berchowitz LE, Copenhaver GP (2008) Fluorescent Arabidopsis tetrads: A visual assay for quickly developing large crossover and crossover interference datasets.  Nature Protocols 3(1): 41-50.  doi:10.1038/nprot.2007.491 *

* This work was featured on the cover.

Copenhaver GP and Hooykaas PJJ (2007) Plant DNA Repair and Recombination on the French Mediterranean.  EMBO Reports 8:1115-9.  doi:10.1038/sj.embor.7401123

Carlson SR, Rudgers GW, Zieler H, Mach JM, Luo S, Grunden E, Krol C, Copenhaver GP, Preuss D (2007) Meiotic transmission of an in vitro-assembled autonomous maize mini-chromosome.  PLoS Genetics 3(10): e179 doi:10.1371/journal.pgen.0030179 *

* This work was featured in a Scientific News article entitled “Artificial Chromosome Poised to Pump Up GM Crops with Extra Genes” (Minkel, JR, 10/23/2007).  It was also featured in an article in The News & Observer newspaper article entitled “Is Gene Stacking the Next Big Thing” (Simmons, T, 10/19/2007)

Berchowitz LE, Francis KE, Bey AL, Copenhaver GP (2007) The Role of AtMUS81 in Interference-Insensitive Crossovers in A. thaliana.  PLoS Genetics 3(8): e132. doi:10.1371/journal.pgen.0030132

Sandaklie-Nikolova L, Palanivelu R, King E, Copenhaver GP, Drews GN (2007) Synergid Cell Death in Arabidopsis is Triggered Following Direct Interaction with the Pollen Tube.  Plant Physiology 144: 1753-1762. doi:10.1104/pp.107.098236

Francis KE, Lam SY, Harrison BD, Bey AL, Berchowitz LE and Copenhaver GP (2007) Pollen Tetrad-based Visual Assay for Meiotic Recombination in Arabidopsis.  Proc. Natl. Acad. Sci.104: 3913-3918.  doi:10.1073/pnas.0608936104 *

* This work was featured in a commentary entitled “Meiosis in Living Color:  Fluorescence-based tetrad analysis in Arabidopsis” (Hawley RS, 2007, PNAS 104: 3673-3674). It was also featured in a research highlight entitled “Full-color Crossovers” (Packer A, 2007, Nature Genetics 39: 449) and in a Nature Genetics “Touching Base” column entitled “Mutant of the month” (Packer A, 2007, Nature Genetics 39: 447).  It was recommended by Faculty of 1000.

Francis KE, Berchowitz LE, Copenhaver GP (2006) Separation of Arabidopsis Pollen Tetrads is Regulated by QRT1, a Pectin Methylesterase Gene.  Plant Physiology 142: 1004-1013.  doi:10.1104/pp.106.085274

Copenhaver GP (2006) A Meiotic Tapas Menu.  PLoS Genetics2(2): e19. doi:10.1371/journal.pgen.0020019

Lam S, Horn SR, Radford SJ, Housworth EA, Stahl FW and Copenhaver GP (2005) Crossover interference on the NOR bearing chromosomes of ArabidopsisGenetics 170(2): 807-812.  doi:10.1534/genetics.104.040055

Copenhaver GP (2005) Plant Genetics: When Not to InterfereCurrent Biology 15(8): R290-1.  doi:10.1016/j.cub.2005.04.007

Copenhaver GP (2005) A Compendium of Plant Species Producing Pollen Tetrads.  J. N. Carolina Acad. of Sci. 121(1): 17-35

Copenhaver GP (2004) Who's driving the centromere? Journal of Biology 3(4):17.  doi:10.1186/jbiol15

Stahl FW, Foss HM, Young LS, Borts RH, Abdullah MFF and Copenhaver GP (2004) Does Crossover Interference Count in Saccharomyces cerevisiae? Genetics 168(1): 35-48.  doi:10.1534/genetics.104.027789 *

* This work was featured in the GENEtics newsletter 1(2): 3.

Hall A, Hall S, Keith K, Copenhaver GP, Preusss D (2004) The rapidly evolving field of plant centromere.  Curr. Op. Plant Biol. 7(2)108-14.  doi:10.1016/j.pbi.2004.01.008

Copenhaver GP (2003) Using Arabidopsis to understand centromere function: Progress and prospects.  Chromosome Research 11(3):255-62.  doi:10.1023/A:1022887926807

Chang Y-L, Henriquez X, Copenhaver GP, Preuss D, and Zhang H-B (2003) A Plant Transformation-competent Binary BAC (BIBAC) library from the Landsberg ecotype of Arabidopsis thaliana.  Theoretical and Applied Genetics 106(2):269-76.  doi:10.1007/s00122-002-1074-2

Krysan PJ,. Young JC,. Jester PJ, Monson S, Copenhaver G, Preuss D, and Sussman MR (2002).  Characterization of T-DNA Insertion Sites in Arabidopsis thaliana and the Implications for Saturation Mutagenesis.  Omics 6(2):163-74.  doi:10.1089/153623102760092760

Copenhaver GP, Housworth E, Stahl FS (2002) Crossover Interference in Arabidopsis.  Genetics 160(4):1631-9.  PMID: 11973316

The Arabidopsis Genome Initiative: Genome Sequencing Groups:  Kaul S, Koo HL, Jenkins J, Rizzo M, Rooney T, Tallon LJ, FeldblyumT, Nierman W, Benito M-I, Lin X, Town CD, Venter JC, Fraser CM, Tabata S, Nakamura Y, Kaneko T, Sato S, Asamizu E, Kato T, KotaniH, Sasamoto S, Ecker JR, Theologis A, Federspiel NA, Palm CJ, Osborne BI, Shinn P, Conway AB, Vysotskaia VS, Dewar K, Conn L, Lenz CA, Kim CJ, Hansen NF, LiuSX, Buehler E, Altafi H, Sakano H, Dunn P, Lam B, Pham PK, Chao Q, Nguyen M, Yu G, Chen H, Southwick A, Lee JM, Miranda M, Toriumi MJ, Davis RW, Wambutt R, Murphy G, Düsterhöft A, Stiekema W, Pohl T, Entian K-D, Terryn N, Volckaert G, Salanoubat M, Choisne N, Rieger M, Ansorge W, Unseld M, Fartmann B, Valle G, Artiguenave F, Weissenbach J, Quetier F, Wilson R, de la Bastide M, Sekhon M, Huang E, Spiegel L, Gnoj L, Pepin K, Murray J, Johnson D, Habermann K, Dedhia N, Parnell L, Preston R, Hillier L, Chen E, Marra M, Martienssen R, McCombie WR, Genome Analysis Group:  Mayer K, White O, Bevan M, Lemcke K, Creasey TH, Bielke C, Haas B, Haase D, Maiti R, Rudd S, Peterson J, Schoof H, Frishman D, Morgenstern B, Zaccaria P, ErmolaevaM, Pertea M, Quackenbush J, Volfovsky N, Wu D, Lowe T, Salzberg SL, Mewes H-W, Contributing Authors:  Rounsley S, Bush D, Subramaniam S, Levin I, Norris S, Schmidt R, Acarkan A, Bancroft I, Quetier F, Brennicke A, Eisen JA, Bureau T, Legault B-A, Le Q-H, Agrawal N, Yu Z, Martienssen R, Copenhaver GP, Luo S, Pikaard CSPreuss D, Paulsen IT, Sussman M, Britt A, SelingerDA, Pandey R, Mount DW, Chandler VL, Jorgensen RA, Juergens G, Meyerowitz EM, Ecker JR, Theologis A, Dangl J & Jones JDG, Chen M, Chory J, and Somerville C.(2000) Analysis of the genome sequence of the flowering plant Arabidopsis thaliana.  Nature 408(6814):796-815.  doi:10.1038/35048692 *

* This work was featured on the cover, and our contribution was also highlighted in “A Journey to the Center of the Chromosome” (C. Mlot, 2000, Science 290:2057-2059).

Copenhaver GP, Keith KC, Preuss D (2000) Tetrad Analysis in Higher Plants: A Budding Technology.  Plant Physiology 124(1):7-16.  doi:10.1104/pp.124.1.7 *

* An illustration from this paper was used as the cover of the issue

Copenhaver GP, Nickel K, Kuromori T., Benito M-I, Kaul S, Lin X, Bevan M, Murphy G, Harris B, Parnell LD, McCombie WR, Martienssen RA, Marra M, Preuss D (1999) Genetic Definition and Sequence Analysis of Arabidopsis Centromeres.  Science 286(5449):2468-74.  doi:10.1126/science.286.5449.2468

Lin X, Kaul S, Rounsley S, Shea TP, Benito M-I, Town CD, Fujii CY, Mason T, Bowman CL, Barnstead M, Feldblyum T, Buell CR, Ketchum KA, Ronning CM, Koo H, Moffat K, Cronin L, Shen M, Pai G, Van Aken S, Umayam L, Tallon L, Gill J, Adams MD, Carrera AJ, Creasy TH, Goodman, HM, Somerville CR, Copenhaver GP, Preuss D., Nierman WC, White O, Eisen JA, Salzberg S, Fraser, CM, Venter JC (1999) Sequence and Analysis of Chromosome 2 of Arabidopsis thaliana. Nature 402(6763):761-8.  doi:10.1038/45471 *

 * This work was featured in a cover caption

Copenhaver GP, Preuss D. (1999) Centromeres in the genomic era:  Unraveling paradoxes.  Curr. Op. Plant Biol. 2(2):104-8.  doi:10.1016/S1369-5266(99)80021-1

Copenhaver GP, Browne WE, Preuss D (1998) Assaying genome-wide recombination and centromere functions with Arabidopsis tetrads. Proc. Natl. Acad. Sci 95(1):247-52.  PMID: 9419361

Copenhaver GP, Pikaard CS (1996) Pulsed-field gel electrophoresis of Arabidopsis thaliana chromosomal DNA.  Weeds World 3(i): 17-2.

Copenhaver GP, Doelling JH, Gens SJ, Pikaard (1995) Use of RFLPs larger than 100 kbp to map the position and internal organization of the nucleolus organizer region on chromosome 2 in Arabidopsis thaliana. The Plant Journal 7(2):273-86.  doi:10.1046/j.1365-313X.1995.7020273.x

Putnam CD, Copenhaver GP, Denton M, Pikaard CS (1994 ) The RNA polymerase I transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap and positively supercoil enhancer DNA. Molecular and Cellular Biology 14(10):6476-88.  doi: 10.1128/MCB.14.10.6476

 Copenhaver GP, Putnam CD, Denton M, Pikaard CS (1994) The RNA polymerase I transcription factor UBF is a sequence-tolerant HMG-box protein that can recognize structured nucleic acids. Nucleic Acids Research 22(13): 2651-2657.  doi:10.1093/nar/22.13.2651

 Ancillary Publications (non-indexed)

Copenhaver GP (2015) Everyone is Biased and Conflicted, Now What? Web blog post. Plant Science Today. ASPB, 28 Sept. 2015.

Copenhaver GP (2015) Do GMOs Accelerate Pesticide Resistance? Web blog post. Feed The Dialog. North Carolina Animal Agricultural Coalition, 1 Nov. 2015.

Copenhaver GP (2014) Meiosis Gordon Conference.  Web blog post.  PLOS Biologue.  PLOS Blogs, 30 May, 2014. 

Copenhaver GP (2005) "Letter from the President." North Carolina Academy of Science Newsletter, Spring 2005. North Carolina Academy of Science. Web.